Rationalizing thrombophilia screening in children: Insights from a 2019 retrospective study at a tertiary care hospital
Thrombophilia testing in children should be carefully targeted, guided by established recommendations, and reserved for situations with clear clinical relevance. Testing should be deferred during acute illness, repeated to confirm lifelong diagnoses, and, if confirmed, accompanied by appropriate preventive counseling. Efforts should also focus on providing standardized, practical advice when a thrombophilia is identified.
Authors
- Hélène Lapillonne (ORCID: https://orcid.org/0000-0002-6900-8313)
- Sébastien Heritier (ORCID: https://orcid.org/0000-0003-0384-6370)
- Raphaël Vialle
- L. Foix‐L’Hélias (ORCID: https://orcid.org/0000-0002-5699-4839)
- Hélène Boutroux
- Sabine Irtan
- Patrick Tounian
- Muriel Houang
- Emmanuel Grimprel
- Tim Ulinski
- Arnaud Petit
- Guillaume Nguyen
- Annie Harroche
- Diana Rodriguez
- Isabelle Constant
- Pierre-Louis Leger
- Manon Leleu
Institutions
- Hôpital Necker-Enfants Malades (FR)
- Université Paris Cité (FR)
- Sorbonne Université (FR)
- Institut Necker Enfants Malades (FR)
- Hôpital Armand-Trousseau (FR)
- Sorbonne Paris Cité (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Laboratoire National de Référence (MA)
- Centre de Recherche Épidémiologie et Statistique (FR)
Publication Details
- Journal
- Archives de Pédiatrie
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1016/j.arcped.2025.12.003
- Primary Topic
- Blood Coagulation and Thrombosis Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00