The Intersections of Fetal Alcohol Syndrome with Autism Spectrum Disorder and Mood Dysregulation: A Rare Case of Behavioral Complexity

This case report presents a complex psychiatric profile of a 19-year-old female with diagnoses of Fetal Alcohol Syndrome (FAS), Autism Spectrum Disorder (ASD), Attention-Deficit/Hyperactivity Disorder (ADHD), mild intellectual disability, and mood dysregulation, complicated by trauma history, psychotic features, and repeated hospitalizations. Her neurodevelopmental and psychiatric disorders have contributed to persistent high-risk behaviors, legal involvement, and challenges with independent living, ultimately necessitating group home placement. This case highlights the unique relationship between FAS and coexisting neurodevelopmental conditions, emphasizing the poor long-term outcomes frequently associated with FAS and ultimately the importance of comprehensive, multidisciplinary care in managing such patients. We review the current literature on co-occurrence of ASD and FAS, prognosis, and clinical management challenges posed by these overlapping conditions.

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Publication Details

Journal
Psychopharmacology Bulletin
Published
2025-12-22
DOI
https://doi.org/10.64719/pb.15437
Primary Topic
Prenatal Substance Exposure Effects
Type
article
Field-Weighted Citation Impact
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article

The Intersections of Fetal Alcohol Syndrome with Autism Spectrum Disorder and Mood Dysregulation: A Rare Case of Behavioral Complexity

Parsa Khaksar, Anuradha Reddy
Psychopharmacology Bulletin
Prenatal Substance Exposure Effects
article

The Intersections of Fetal Alcohol Syndrome with Autism Spectrum Disorder and Mood Dysregulation: A Rare Case of Behavioral Complexity

Parsa Khaksar, Anuradha Reddy
article en

Abstract

This case report presents a complex psychiatric profile of a 19-year-old female with diagnoses of Fetal Alcohol Syndrome (FAS), Autism Spectrum Disorder (ASD), Attention-Deficit/Hyperactivity Disorder (ADHD), mild intellectual disability, and mood dysregulation, complicated by trauma history, psychotic features, and repeated hospitalizations. Her neurodevelopmental and psychiatric disorders have contributed to persistent high-risk behaviors, legal involvement, and challenges with independent living, ultimately necessitating group home placement. This case highlights the unique relationship between FAS and coexisting neurodevelopmental conditions, emphasizing the poor long-term outcomes frequently associated with FAS and ultimately the importance of comprehensive, multidisciplinary care in managing such patients. We review the current literature on co-occurrence of ASD and FAS, prognosis, and clinical management challenges posed by these overlapping conditions.

Psychopharmacology BulletinVol. 56(1)
Carilion Clinic (US)
No poverty
Openalex Percentile: Top 16%
Prenatal Substance Exposure Effects
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