Investigating Salivary Extracellular Vesicles as Biomarkers for Alzheimer's Disease: ExosomeAD Study Design and Baseline Characteristics

Salivary EVs contain important information about brain health and may be a useful biomarker for AD. However, AD-specific signatures in EVs have not yet been characterized. If successful, the Exosome Study will be first to demonstrate that salivary EV RNA and protein can be used to detect AD and facilitate the development of an inexpensive and noninvasive screening method for use in specialty and primary care settings.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2025-12-01
DOI
https://doi.org/10.1002/alz70856_105183
Primary Topic
Extracellular vesicles in disease
Type
article
Field-Weighted Citation Impact
0.00
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article

Investigating Salivary Extracellular Vesicles as Biomarkers for Alzheimer's Disease: ExosomeAD Study Design and Baseline Characteristics

M. Pereira, Sicheng Wen, Charles Denby, Hannah Alaimo et al.
Alzheimer s & Dementia
Extracellular vesicles in disease
article

Investigating Salivary Extracellular Vesicles as Biomarkers for Alzheimer's Disease: ExosomeAD Study Design and Baseline Characteristics

M. Pereira, Sicheng Wen, Charles Denby, Hannah Alaimo, Jill A. Kreiling, E.M. Teixeira, Peter J. Quesenberry, Jonathan D. Drake, Victoria Sanborn, Jenna R Pracht, Lori A. Daiello
article en

Abstract

Salivary EVs contain important information about brain health and may be a useful biomarker for AD. However, AD-specific signatures in EVs have not yet been characterized. If successful, the Exosome Study will be first to demonstrate that salivary EV RNA and protein can be used to detect AD and facilitate the development of an inexpensive and noninvasive screening method for use in specialty and primary care settings.

Alzheimer s & DementiaVol. 21(S2)
Providence College (US), Brown University (US), Rhode Island Hospital (US)
Openalex Percentile: Top 34%
Extracellular vesicles in disease
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Investigating Salivary Extracellular Vesicles as Biomarkers for Alzheimer's Disease: ExosomeAD Study Design and Baseline Characteristics — M. Pereira, Sicheng Wen, et al. · Alzheimer s & Dementia (2025) | TGRS Research Map | TGRS