Investigating Salivary Extracellular Vesicles as Biomarkers for Alzheimer's Disease: ExosomeAD Study Design and Baseline Characteristics
Salivary EVs contain important information about brain health and may be a useful biomarker for AD. However, AD-specific signatures in EVs have not yet been characterized. If successful, the Exosome Study will be first to demonstrate that salivary EV RNA and protein can be used to detect AD and facilitate the development of an inexpensive and noninvasive screening method for use in specialty and primary care settings.
Authors
- M. Pereira
- Sicheng Wen (ORCID: https://orcid.org/0000-0002-4428-3634)
- Charles Denby
- Hannah Alaimo
- Jill A. Kreiling (ORCID: https://orcid.org/0000-0003-4440-2039)
- E.M. Teixeira
- Peter J. Quesenberry
- Jonathan D. Drake
- Victoria Sanborn
- Jenna R Pracht
- Lori A. Daiello
Institutions
- Providence College (US)
- Brown University (US)
- Rhode Island Hospital (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_105183
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00