Mn(III)-Mediated Cascade Arylation/Cyclization of <i>Ortho-</i> (propargylamino) Aryl Isocyanides with Aryl Boronic Acids: Access to Tetracyclic Benzo[ <i>b</i> ]indeno[1,2- <i>e</i> ][1,4]diazepines
A Mn(III)-promoted cascade arylation/cyclization of <i>ortho</i>-isocyano propargylanilines with aryl boronic acids has been developed. The protocol provides a novel and highly efficient access to construct two central rings (diazepine and cyclopenta-1,3-diene) of a tetracyclic product via the formation of three C-C bonds in one pot.
Authors
- Puying Luo (ORCID: https://orcid.org/0000-0002-0672-5462)
- Hong Yan (ORCID: https://orcid.org/0000-0003-3993-0013)
- Kelin Yang
- Liu Yang
- Qiuping Ding
- Yiyuan Peng
Institutions
- Jiangxi Maternal and Child Health Hospital (CN)
- Chemical Synthesis Lab (SG)
- Jiangxi Normal University (CN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2026-01-09
- DOI
- https://doi.org/10.1021/acs.joc.5c02589
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00