Cerebrospinal Fluid Proteins as Biomarkers of Brain Vascular Injury

Vascular disease can co-occur with AD. Our results show associations between CSF proteins involved in structural integrity and chemical signaling and CA in a sample with impaired and normal cognition. Further, we detected racial differences in these associations. Given these findings among cognitively normal and impaired people, these proteins may have promise as early disease indicators. More extensive study with a larger sample is needed.