Evaluation of the Effect of Intravenous Lidocaine on the Systemic Inflammatory Response Associated With Cardiopulmonary Bypass in Valvular and/or Coronary Cardiac Surgery: Protocol for a Double-Blind Randomized Clinical Trial

This trial will determine whether intravenous lidocaine attenuates the systemic inflammatory response induced by CPB and improves clinical outcomes in adult patients undergoing elective cardiac surgery.

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Publication Details

Journal
Journal of Cardiothoracic and Vascular Anesthesia
Published
2026-01-01
DOI
https://doi.org/10.1053/j.jvca.2026.01.008
Primary Topic
Cardiac and Coronary Surgery Techniques
Type
article
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article

Evaluation of the Effect of Intravenous Lidocaine on the Systemic Inflammatory Response Associated With Cardiopulmonary Bypass in Valvular and/or Coronary Cardiac Surgery: Protocol for a Double-Blind Randomized Clinical Trial

A Fernández-Martínez, J González-García, P de Miguel Fernández, B Castroviejo Ibáñez et al.
Journal of Cardiothoracic and Vascular Anesthesia
Cardiac and Coronary Surgery Techniques
article

Evaluation of the Effect of Intravenous Lidocaine on the Systemic Inflammatory Response Associated With Cardiopulmonary Bypass in Valvular and/or Coronary Cardiac Surgery: Protocol for a Double-Blind Randomized Clinical Trial

A Fernández-Martínez, J González-García, P de Miguel Fernández, B Castroviejo Ibáñez, S Valero González, GalveAI Marqués, M Íñiguez Martínez, P Benito Martínez, A Bermejo Bravo, R Apiñaniz Apiñaniz, A López Picado, F Lobato Solores, L Ferreira Laso, M Aguado Sevilla, N Boukichou Abdelkader, E Corral Cárdenas, I Mainar Gil
article en

Abstract

This trial will determine whether intravenous lidocaine attenuates the systemic inflammatory response induced by CPB and improves clinical outcomes in adult patients undergoing elective cardiac surgery.

Journal of Cardiothoracic and Vascular Anesthesia
University of the Basque Country (ES), Basque Government (ES), Hospital de Basurto (ES), Hospital San Pedro (ES), Center for Biomedical Research of La Rioja (ES)
Good health and well-being
Openalex Percentile: Top 93%
Cardiac and Coronary Surgery Techniques
DOIOpen Access PDFOpenAlex
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Evaluation of the Effect of Intravenous Lidocaine on the Systemic Inflammatory Response Associated With Cardiopulmonary Bypass in Valvular and/or Coronary Cardiac Surgery: Protocol for a Double-Blind Randomized Clinical Trial — A Fernández-Martínez, J González-García, et al. · Journal of Cardiothoracic and Vascular Anesthesia (2026) | TGRS Research Map | TGRS