Concurrent Detection of Cognitive Impairment and Amyloid‐Beta PET Status with a Combination of Digital Clock and Recall and Digital Trail Making Test‐Part B

A multimodal model combining process-based features of DCR and dTMT-B had very good to excellent performance in cognitive-impairment detection and excellent performance in Aβ-PET status prediction, with the DCR+dTMT-B+APOE model performing comparably to CSF biomarkers of AD. This model enables prioritizing the most suitable patients for BBM testing and DMTs, and substantially increases the efficiency of recruitment for AD clinical trials.