Head‐to‐head in vivo Braak staging with MK6240 and Flortaucipir
These preliminary findings reveal some discrepancies in Braak staging when comparing MK6240 and Flortaucipir. Our results also suggest that adjustments in cutoffs and regions of interest can partially mitigate both inter- and intra-tracer divergences. Finally, our analysis suggests robust concordance after adjustment and using 4 classes (0, I-II, III-IV, V-VI).
Authors
- DL Tudorascu
- Joseph C. Masdeu (ORCID: https://orcid.org/0000-0001-9955-6954)
- Guilherme Bauer‐Negrini (ORCID: https://orcid.org/0000-0003-0956-557X)
- Emma Patrice Ruppert (ORCID: https://orcid.org/0000-0001-5877-5472)
- Matheus Scarpatto Rodrigues (ORCID: https://orcid.org/0000-0002-7794-6588)
- Suzanne L. Baker (ORCID: https://orcid.org/0000-0003-0209-3127)
- Firoza Zubeida Lussier (ORCID: https://orcid.org/0000-0002-6877-4825)
- Juan M. Fortea (ORCID: https://orcid.org/0000-0002-1340-638X)
- VJ Lowe (ORCID: https://orcid.org/0000-0002-5612-1667)
- Pamela C.L. Ferreira
- Livia Amaral
- Carolina Soares
- Andreia Rocha
- David N. Soleimani‐Meigooni
- Marina Scop Madeiros
- Bruna Bellaver
- Brian A. Gordon
- Hwamee Oh
- Belen Pascual
- Guilherme Povala
- Pedro Rosa‐Neto
Institutions
- Houston Methodist (US)
- Lawrence Berkeley National Laboratory (US)
- University of Pittsburgh (US)
- University of California, San Francisco (US)
- Washington University in St. Louis (US)
- Brown University (US)
- Hospital de Sant Pau (ES)
- Mayo Clinic in Arizona (US)
- McGill University (CA)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_107534
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00