Assessment of the integrity of real-time electronic health record data used in clinical research

This study demonstrates the feasibility of automated benchmarking to assess the integrity of real-time EHR data and identify when such data become analysis ready. Our findings highlight key challenges for secondary use of dynamic clinical data and provide an automated framework that can be applied across health systems to support high-quality research, surveillance, and clinical trial readiness.

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Publication Details

Journal
PLoS ONE
Published
2026-01-09
DOI
https://doi.org/10.1371/journal.pone.0340287
Primary Topic
Electronic Health Records Systems
Type
article
Field-Weighted Citation Impact
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article

Assessment of the integrity of real-time electronic health record data used in clinical research

Andreas Coppi, Guannan Gong, Sameer Pandya, Jessica Liu et al.
PLoS ONE
Electronic Health Records Systems
article

Assessment of the integrity of real-time electronic health record data used in clinical research

Andreas Coppi, Guannan Gong, Sameer Pandya, Jessica Liu, Harlan M. Krumholz, H. Patrick Young, Wade L. Schulz
article en

Abstract

This study demonstrates the feasibility of automated benchmarking to assess the integrity of real-time EHR data and identify when such data become analysis ready. Our findings highlight key challenges for secondary use of dynamic clinical data and provide an automated framework that can be applied across health systems to support high-quality research, surveillance, and clinical trial readiness.

PLoS ONEVol. 21(1)
Yale New Haven Hospital (US), Yale Cancer Center (US), Yale University (US), Yale New Haven Health System (US)
Quality Education
Openalex Percentile: Top 93%
Electronic Health Records Systems
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