Lymphoma in Meckel cave mimicking trigeminal schwannoma – analysis of misdiagnosis causes and insights into imaging: Case report

The "perineural growth" pattern and "dumbbell" morphology of this Meckel cave lymphoma were highly deceptive and directly led to misdiagnosis. Lymphoma should be critically included in the differential diagnosis for Meckel cave lesions presenting with rapid progression (<6 months), schwannoma-like imaging features, and absence of prominent T2 hyperintensity. Preoperative cerebrospinal fluid analysis or targeted biopsy can prevent unnecessary surgical interventions and ensure timely administration of standardized chemotherapy.

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Publication Details

Journal
Medicine
Published
2026-01-09
DOI
https://doi.org/10.1097/md.0000000000047137
Primary Topic
Meningioma and schwannoma management
Type
article
Field-Weighted Citation Impact
0.00
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article

Lymphoma in Meckel cave mimicking trigeminal schwannoma – analysis of misdiagnosis causes and insights into imaging: Case report

Q ZHANG, Wenbo Liu, Qiang Li, Chengxin Yan et al.
Medicine
Meningioma and schwannoma management
article

Lymphoma in Meckel cave mimicking trigeminal schwannoma – analysis of misdiagnosis causes and insights into imaging: Case report

Q ZHANG, Wenbo Liu, Qiang Li, Chengxin Yan, Tong Zhang
article en

Abstract

The "perineural growth" pattern and "dumbbell" morphology of this Meckel cave lymphoma were highly deceptive and directly led to misdiagnosis. Lymphoma should be critically included in the differential diagnosis for Meckel cave lesions presenting with rapid progression (<6 months), schwannoma-like imaging features, and absence of prominent T2 hyperintensity. Preoperative cerebrospinal fluid analysis or targeted biopsy can prevent unnecessary surgical interventions and ensure timely administration of standardized chemotherapy.

MedicineVol. 105(2)
Affiliated Hospital of Taishan Medical University (CN), Shandong First Medical University (CN)
Gender equality
Openalex Percentile: Top 94%
Meningioma and schwannoma management
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