Therapeutic effect of amniotic membrane mesenchymal stem cell-derived exosome-rich conditioned medium in cerebral palsy model
ERCM confers therapeutic benefits in CP by preserving neural stem and oligodendrocyte progenitor cells, modulating apoptosis and inflammation, and enhancing oligodendrocyte differentiation. Accordingly, ERCM may present a good candidate as a CP therapeutic agent.
Authors
- Dongsun Park (ORCID: https://orcid.org/0000-0001-6042-5949)
- Yunseo Choi
- Ehn-Kyoung Choi
- Yun-Bae Kim
- Dae Hwan Kim
- Eun-Jung Yoon
- Jiwon Jeong
- Tae Myoung Kim
Institutions
- Chungbuk National University (KR)
- Kangwon National University (KR)
- Kongju National University (KR)
- Cheongju University (KR)
- CTI BioPharma (Italy) (IT)
Publication Details
- Journal
- Stem Cells Translational Medicine
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1093/stcltm/szaf071
- Primary Topic
- Neonatal and fetal brain pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00