Role of Uterine Artery Doppler in Pregnant Woman at 11 To 24 Weeks of Gestation in Predicting Pre-Eclampsia

Abstract Background: Anticipating preeclampsia’s onset is pivotal in mitigating adverse maternal and perinatal outcomes. This study aims to study the prognosis of preeclampsia within low-risk pregnancies by evaluating uterine artery Doppler indices within the 11-24 week gestation. Methodology: A prospective observational study comprising 68 low-risk pregnancies (11-24 weeks gestation) underwent serial uterine artery Doppler assessments at 11-24 and 20-284weeks. Follow-up was extended to delivery to detect preeclampsia incidence. Results: Among 68 participants, 13 (19.1%) developed preeclampsia. Sensitivity values for resistance index (RI), pulsatility index (PI), and bilateral notching were 23.1%, 46.2%, and 61.5%, respectively, during 11-14 weeks. Similarly, during 20-24 weeks, sensitivities for RI, PI, and bilateral notching were 23.1%, 38.5%, and 61.5%, respectively, with specificity exceeding 100%. Conclusions: Bilateral notching during 11-14 weeks and integrated doppler markers within 11-14 and 20-28 weeks indicate preeclampsia susceptibility in low-risk pregnancies. Conversely, uterine artery Doppler indices at 11-24 weeks effectively rule out preeclampsia development, exhibiting a specificity of >90%. Categories: Obstetrics/Gynecology, Radiology