Replacement fibrosis, left ventricular ejection fraction and sudden cardiac death in patients after myocardial infarction: a mediation analysis
LVEF partially mediated the effect of LGE on the SCD, accounting for less than one-fifth of the total effect. LVEF alone inadequately captured the whole SCD risk, irrespective of whether LVEF is greater than 35% or 35% or less.
Authors
- Zhuxin Wei (ORCID: https://orcid.org/0000-0001-8053-7120)
- Xiuyu Chen (ORCID: https://orcid.org/0000-0002-9432-6081)
- X Y Chen
- Pengyu Zhou (ORCID: https://orcid.org/0000-0001-9719-067X)
- Shujuan Yang (ORCID: https://orcid.org/0000-0003-2302-004X)
- Minjie Lu (ORCID: https://orcid.org/0000-0002-4358-8073)
- Fengnian Zhao
- X. Zhao
- Wenqing Xu (ORCID: https://orcid.org/0000-0001-8199-9693)
- Kaisaierjiang Aisikaier
- Fen Sa (ORCID: https://orcid.org/0009-0008-8813-8843)
- Jiaxin Wang
- Xi Jia
- Yujie Liu
- Zhixiang Dong
- Shihua Zhao
- Yun Tang
- Xuan Ma
Institutions
- Capital Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking University (CN)
- Sichuan University (CN)
- Kunming Medical University (CN)
- Peking Union Medical College Hospital (CN)
- West China Second University Hospital of Sichuan University (CN)
- Beijing Anzhen Hospital (CN)
- Peking University People's Hospital (CN)
Publication Details
- Journal
- Open Heart
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1136/openhrt-2025-003799
- Primary Topic
- Cardiac Imaging and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China