The Impact of Early Life Bilateral Salpingo‐Oophorectomy on the Nucleus Basalis of Meynert
Preliminary findings suggest that aging and early-BSO may influence basal forebrain structure. Future work should disentangle age/time-since-BSO from estradiol loss. It might also investigate further memory circuit disruption by examining surrounding cholinergic white matter pathways further identifying early AD biomarkers.
Authors
- Alana Brown (ORCID: https://orcid.org/0000-0002-1237-1314)
- Laura L. Gravelsins (ORCID: https://orcid.org/0000-0002-9087-9199)
- Sai Zhao (ORCID: https://orcid.org/0000-0001-9362-6835)
- Annie Duchesne (ORCID: https://orcid.org/0000-0001-6049-8785)
- Gillian Einstein (ORCID: https://orcid.org/0000-0002-0770-5471)
- Shreeyaa Ramana (ORCID: https://orcid.org/0009-0006-9010-6184)
- Nicole J. Gervais
- Natasha Rajah
- Noelia Calvo
- Cheryl Grady
- Zaki Ul Haq
Institutions
- Centre for Addiction and Mental Health (CA)
- University of Northern British Columbia (CA)
- University of Groningen (NL)
- University of Toronto (CA)
- Women's College Hospital (CA)
- Baycrest Hospital (CA)
- Metropolitan University (RS)
- McGill University (CA)
- Université du Québec à Trois-Rivières (CA)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/alz70856_106937
- Primary Topic
- Menopause: Health Impacts and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00