Multi-omics and perturbation screens as discovery tools in immunometabolism

Metabolic rewiring of immune cells has broad impacts on immune responses and disease outcomes. Systems biology approaches, such as multi-omics profiling and perturbation screening, could uncover new actionable targets and therapeutic avenues to explore.

Authors

Nicole M. Chapman (ORCID: https://orcid.org/0000-0003-4710-1776)
Hongbo Chi

Institutions

St. Jude Children's Research Hospital (US)

Publication Details

Journal: PLoS Biology
Published: 2026-01-09
DOI: https://doi.org/10.1371/journal.pbio.3003570
Citations: 1
Primary Topic: Single-cell and spatial transcriptomics
Type: article
Field-Weighted Citation Impact: 22.24

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article

Multi-omics and perturbation screens as discovery tools in immunometabolism

Nicole M. Chapman, Hongbo Chi

Jan 9, 2026

1 citations

PLoS Biology

Single-cell and spatial transcriptomics

22.24

article

Multi-omics and perturbation screens as discovery tools in immunometabolism

Nicole M. Chapman, Hongbo Chi

January 9, 2026article en

1 citations

Abstract

PLoS BiologyVol. 24(1)

St. Jude Children's Research Hospital (US)

Good health and well-being

Openalex Percentile: Top 3%

Single-cell and spatial transcriptomics

22.24

DOI Open Access PDF OpenAlex

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Multi-omics and perturbation screens as discovery tools in immunometabolism — Nicole M. Chapman, Hongbo Chi · PLoS Biology (2026) | TGRS Research Map | TGRS