Association of EEG Response to Hypertonic Saline and Neurologic Outcomes in Pediatric Acute Brain Injury
An ADR increase > 20% following HTS was associated with increased odds of survival with favorable neurologic outcome and survival to hospital discharge in critically ill pediatric patients with acute brain injury. qEEG response to HTS may serve as a real-time, noninvasive biomarker of cerebral perfusion responsiveness.
Authors
- Clare Press
- Arastoo Vossough (ORCID: https://orcid.org/0000-0003-1346-427X)
- Raymond Liu (ORCID: https://orcid.org/0000-0002-4667-9632)
- Eva Catenaccio (ORCID: https://orcid.org/0000-0003-0550-207X)
- Julie A. Kurek
- Shih-shan Lang
- Emma L. Mazzio
- Jimmy W. Huh
- Robert A. Berg
- Alexis A. Topjian
Institutions
- Children's Hospital of Philadelphia (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Neurocritical Care
- Published
- 2026-01-08
- DOI
- https://doi.org/10.1007/s12028-025-02422-x
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 0.00