Clinical Assessment of the Effect of <i>Hypericum perforatum</i> Chewing Gum on Salivary <i>Streptococcus mutans</i> Count, pH, Plaque Index, and Gingival Bleeding: A Randomized Clinical Trial
Our results revealed gum formulation of H. perforatum extract had significant effects on lowering salivary Streptococci mutans count, plaque index, and gingival bleeding compared to gum without extract group as well as their amounts before gum use. Although both gums elevated salivary pH, there was no statistically significant difference in short-term measurements. Under the conditions of this study, H. perforatum gum can be considered a promising adjutant for oral health improvement.
Authors
- Seyedeh Elham Mousavi Kalajahi
- Maryam Kouhsoltani (ORCID: https://orcid.org/0000-0002-0786-0690)
- Mohammad Yousef Memar (ORCID: https://orcid.org/0000-0002-0328-4753)
- Hamed Hamishehkar
- Aylin Jamali
- Morteza Kosari‐Nasab
Institutions
- Khazar University (AZ)
- Tabriz University of Medical Sciences (IR)
- University of Tabriz (IR)
Publication Details
- Journal
- Clinical and Experimental Dental Research
- Published
- 2026-01-09
- DOI
- https://doi.org/10.1002/cre2.70285
- Citations
- 1
- Primary Topic
- Natural Compound Pharmacology Studies
- Type
- article
- Field-Weighted Citation Impact
- 31.34
Funders
- Tabriz University of Medical Sciences
- University of Tabriz