Targeting Melasma: Innovations in Pigment Deposition and Photoaging in Cosmetic Dermatology

Melasma management is evolving toward multi-target, combination-based strategies addressing pigmentation, inflammation, and photoaging simultaneously. Emerging regenerative technologies, biomarker-driven personalization, and AI-assisted assessment hold promise for improving long-term outcomes, though standardized protocols and long-term safety data are still needed.