Mebendazole inhibits PELI3-mediated ubiquitination of TRADD in non-small cell lung cancer cells
PELI3 can function as an E3 ubiquitin ligase to ubiquitinate TRADD, and Mebendazole might be a promising drug to affect PELI3 expression in NSCLC.
Authors
- Fannian Li
- X Li
- Haitao Li (ORCID: https://orcid.org/0000-0002-3740-571X)
- Yuzheng He
- Xianhua Bai
- Tianjie Qi
- Yanchao Liu (ORCID: https://orcid.org/0000-0002-9787-9749)
- Xiumin Zhao
- Shuai Li
Institutions
- Hebei Medical University (CN)
- Second Hospital of Hebei Medical University (CN)
- Hebei General Hospital (CN)
- Xingtai People's Hospital (CN)
- First Affiliated Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-01-09
- DOI
- https://doi.org/10.3389/fonc.2025.1728170
- Primary Topic
- Cell death mechanisms and regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Health Commission of Hebei Province
- Hebei Medical University