Electroacupuncture ameliorates incisional pain via suppressing IL-33 signaling-related macrophage infiltration and ROS overproduction in incised skin
These results demonstrate that EA ameliorates incisional pain via suppressing IL-33 overproduction in incised skin tissue. EA-induced suppression of IL-33 overproduction results in less macrophage infiltration and ROS accumulation that contribute to analgesia. Our work helps to support EA as an alternative and green therapy for postoperative pain management.
Authors
- Peiyi Li (ORCID: https://orcid.org/0000-0002-2380-2562)
- Guihua Tian (ORCID: https://orcid.org/0000-0002-5941-2945)
- Jianqiao Fang
- Ruoyao Xu
- Xiaofen He
- Junying Du
- Kaige Zheng
- Boyi Liu
- Yushuang Pan
- Yan Tai
- Muyan Chen
- Boyu Liu
Institutions
- Zhejiang Chinese Medical University (CN)
- The Third Affiliated Hospital of Zhejiang Chinese Medical University (CN)
- Beijing Friendship Hospital (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2026-01-09
- DOI
- https://doi.org/10.1186/s13020-025-01273-0
- Citations
- 1
- Primary Topic
- Acupuncture Treatment Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 51.14