Outcomes of aortic and mitral valve replacement with Dafodil™ pericardial bioprosthesis over 5-years: Dafodil™-1 trial

Over five years, the bioprosthesis demonstrated sustained haemodynamic performance, clinical safety, and QoL. The absence of SVD and low rates of adverse events encourage its use in young patients requiring surgical valve replacement. Furthermore, a long-term follow-up is warranted to evaluate its durability.

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Publication Details

Journal
Frontiers in Cardiovascular Medicine
Published
2026-01-09
DOI
https://doi.org/10.3389/fcvm.2025.1672315
Primary Topic
Cardiac Valve Diseases and Treatments
Type
article
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article

Outcomes of aortic and mitral valve replacement with Dafodil™ pericardial bioprosthesis over 5-years: Dafodil™-1 trial

Channabasavaraj Shivalingaiah Hiremath, Binay Krishna Sarkar, Atul A. Maslekar, Dhaval Naik et al.
Frontiers in Cardiovascular Medicine
Cardiac Valve Diseases and Treatments
article

Outcomes of aortic and mitral valve replacement with Dafodil™ pericardial bioprosthesis over 5-years: Dafodil™-1 trial

Channabasavaraj Shivalingaiah Hiremath, Binay Krishna Sarkar, Atul A. Maslekar, Dhaval Naik, Chandrasekar Padmanabhan, Yugal Mishra, Anand Sancheti, Subash S. Rajput, Nirmal K. Gupta, Shiv Kumar Chaudhary, Zile Singh Meharwal, Chittaranjan S. J., Seetharama Bhat, Anil Jain, Anurag Garg, Manish Porwal, Nityanand Tukaram Thakur, Prashant Vaijyanath, Vijay Kumar Gupta, Naman Shastri, Vijay Grover
article en

Abstract

Over five years, the bioprosthesis demonstrated sustained haemodynamic performance, clinical safety, and QoL. The absence of SVD and low rates of adverse events encourage its use in young patients requiring surgical valve replacement. Furthermore, a long-term follow-up is warranted to evaluate its durability.

Frontiers in Cardiovascular MedicineVol. 12
Apollo Hospitals (IN), Nil Ratan Sircar Medical College and Hospital (IN), Sanjay Gandhi Post Graduate Institute of Medical Sciences (IN), B. J. Medical College & Sassoon Hospital (IN), Nagpur Institute of Technology (IN), Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital (IN), Care Institute of Medical Sciences (IN), Madras Medical Mission (IN), Sri Jayadeva Institute of Cardiovascular Sciences and Research (IN), Narayana Health (IN), Dr. D. Y. Patil Medical College, Hospital and Research Centre (IN), Fortis Escorts Heart Institute (IN), Kovai Medical Center and Hospital (IN), Sri Sathya Sai Institute of Higher Medical Sciences (IN), Sri Sathya Sai Institute of Higher Medical Sciences (IN), Dr. Ram Manohar Lohia Institute of Medical Sciences (IN), G. Kuppuswamy Naidu Memorial Hospital (IN), Choithram Hospital and Research Centre (IN), Manipal Hospital (IN)
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Cardiac Valve Diseases and Treatments
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