An improved method for recovering clinical isolates and assessing pathogenicity of blood from secondary syphilis patients

This study shows that the pathogenicity of secondary syphilis blood is greater than previously recognized. Thus, monitoring Tp particle agglutination titers enables the recovery of Tp clinical isolates, even from specimens with extremely low bacterial burdens.

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Publication Details

Journal
Sexual Health
Published
2026-01-09
DOI
https://doi.org/10.1071/sh25185
Primary Topic
Syphilis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

An improved method for recovering clinical isolates and assessing pathogenicity of blood from secondary syphilis patients

Litian Zhang, Yinbo Jiang, zhili Hu, Heping Zheng et al.
Sexual Health
Syphilis Diagnosis and Treatment
article

An improved method for recovering clinical isolates and assessing pathogenicity of blood from secondary syphilis patients

Litian Zhang, Yinbo Jiang, zhili Hu, Heping Zheng, Liyan Xi, Xiaohui Zhang, Ligang Yang, Bin Yang
article en

Abstract

This study shows that the pathogenicity of secondary syphilis blood is greater than previously recognized. Thus, monitoring Tp particle agglutination titers enables the recovery of Tp clinical isolates, even from specimens with extremely low bacterial burdens.

Sexual HealthVol. 23(2)
Key Laboratory of Guangdong Province (CN), Southern Medical University (CN)
Good health and well-being
Openalex Percentile: Top 93%
Syphilis Diagnosis and Treatment
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