Impact of Emphysema on Therapeutic Efficacy and Immune-Related Pneumonitis Risk in NSCLC Patients Receiving ICIs: A Meta-Analysis of Improved Survival but Increased Toxicity
Based on available evidence, CT-defined emphysema indicates better therapeutic efficacy with longer PFS and OS, but increased risk of ICIP among NSCLC patients receiving ICIs. These findings suggest emphysema may guide personalized immunotherapy decisions in NSCLC.
Authors
- Wenyi Lan
- Xiaodan Yu (ORCID: https://orcid.org/0000-0003-2283-7138)
- Wenjun Li (ORCID: https://orcid.org/0000-0003-1152-5016)
- Shilan Liu
- Xiao Liu
Institutions
- Chengdu Fifth People's Hospital (CN)
Publication Details
- Journal
- International Journal of COPD
- Published
- 2026-01-01
- DOI
- https://doi.org/10.2147/copd.s569504
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chengdu University of Traditional Chinese Medicine
- Chengdu University
- Sichuan Provincial Administration of Traditional Chinese Medicine