MAPK-related mRNA and miRNA Expression in LPS-treatedKeratinocytes: Implications for Psoriasis Inflammation
LPS stimulation alters MAPK-related mRNA and protein expression in HaCaT cells and is accompanied by changes in specific regulatory miRNAs. This integrative transcriptomic- proteomic analysis highlights candidate miRNA-mRNA axes relevant to psoriasis pathophysiology and supports further validation in disease-relevant models.
Authors
- Beniamin Oskar Grabarek
- nikola zmarzły
- Konrad Kaminiów (ORCID: https://orcid.org/0000-0002-7481-2621)
- Amelia Głowaczewska (ORCID: https://orcid.org/0000-0001-7572-0895)
- Michał Wójcik (ORCID: https://orcid.org/0000-0002-1918-6912)
- Weronika Wieczorek (ORCID: https://orcid.org/0000-0002-1192-3383)
- Michał Chalcarz (ORCID: https://orcid.org/0000-0003-3968-5062)
- Aleksandra Plata-Babula
- Bernadeta Kuraszewska (ORCID: https://orcid.org/0009-0007-8068-3903)
- Elżbieta Mitka-Krysiak
Institutions
- Państwowa Wyższa Szkoła Zawodowa w Nysie (PL)
- WSB University (PL)
Publication Details
- Journal
- Current Pharmaceutical Biotechnology
- Published
- 2026-01-07
- DOI
- https://doi.org/10.2174/0113892010379048251031100323
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00