1-hour post-load plasma glucose: a reliable marker of insulin resistance in type 2 diabetes, as determined by the TyG index

Among T2DM subjects, 1h-PG shows a stronger association with the TyG index than 2h-PG. These findings support the potential of 1h-PG as a more sensitive and cost-effective marker for early identification of insulin resistance, offering clinical utility in diabetes diagnosis and management.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2026-01-09
DOI
https://doi.org/10.3389/fendo.2025.1671040
Primary Topic
Diabetes, Cardiovascular Risks, and Lipoproteins
Type
article
Field-Weighted Citation Impact
0.00

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article

1-hour post-load plasma glucose: a reliable marker of insulin resistance in type 2 diabetes, as determined by the TyG index

Lili Xu, Qiuyue Shen, Chen Chen, Qingyu Guo et al.
Frontiers in Endocrinology
Diabetes, Cardiovascular Risks, and Lipoproteins
article

1-hour post-load plasma glucose: a reliable marker of insulin resistance in type 2 diabetes, as determined by the TyG index

Lili Xu, Qiuyue Shen, Chen Chen, Qingyu Guo, Ting Chen, Jiaqing Shao, Ping Gu, Li Lv, Min Chen, Xinyi Yang
article en

Abstract

Among T2DM subjects, 1h-PG shows a stronger association with the TyG index than 2h-PG. These findings support the potential of 1h-PG as a more sensitive and cost-effective marker for early identification of insulin resistance, offering clinical utility in diabetes diagnosis and management.

Frontiers in EndocrinologyVol. 16
Second Affiliated Hospital of Nanjing Medical University (CN), Nanjing Medical University (CN)
Jiangsu Commission of Health, National Natural Science Foundation of China, Government of Jiangsu Province, Natural Science Foundation of Jiangsu Province
Openalex Percentile: Top 93%
Diabetes, Cardiovascular Risks, and Lipoproteins
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