Prediction of key abnormal biochemical parameters in femoral neck fractures: an AI approach

This study developed several ML-based predictive models that effectively assess changes in perioperative biochemical parameters in patients with femoral neck fractures. The interpretability heatmap clearly indicated the clinical features most influential on each biochemical parameter, such as the close relationship between K* and creatinine, which aligns with kidney regulation mechanisms and existing physiological knowledge. External data validation further demonstrated the model's robustness, suggesting that the model is applicable not only to the existing dataset but also to a broader clinical population. Overall, the proposed model provides an effective tool for perioperative management, with promising potential for clinical practice to help optimise treatment strategies and improve patient outcomes and quality of life.

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Publication Details

Journal
Hip International
Published
2026-01-08
DOI
https://doi.org/10.1177/11207000251400682
Primary Topic
Hip and Femur Fractures
Type
article
Field-Weighted Citation Impact
0.00
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article

Prediction of key abnormal biochemical parameters in femoral neck fractures: an AI approach

Long Li
Hip International
Hip and Femur Fractures
article

Prediction of key abnormal biochemical parameters in femoral neck fractures: an AI approach

Long Li
article en

Abstract

This study developed several ML-based predictive models that effectively assess changes in perioperative biochemical parameters in patients with femoral neck fractures. The interpretability heatmap clearly indicated the clinical features most influential on each biochemical parameter, such as the close relationship between K* and creatinine, which aligns with kidney regulation mechanisms and existing physiological knowledge. External data validation further demonstrated the model's robustness, suggesting that the model is applicable not only to the existing dataset but also to a broader clinical population. Overall, the proposed model provides an effective tool for perioperative management, with promising potential for clinical practice to help optimise treatment strategies and improve patient outcomes and quality of life.

Hip International
Tianjin Medical University (CN)
Openalex Percentile: Top 93%
Hip and Femur Fractures
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