Blood transfusion for patients in shock: devices for collection, transport, and storage

Strict maintenance of temperatures is required to ensure the efficacy and safety of blood components. This can be achieved using active or passive transport systems, known as shippers. Additional storage and transportation considerations include pre-conditioning of cold or frozen bricks, packing construct of protective insulating material, location of blood components in shipper, and labeling of blood transport shippers. Blood components are usually collected and stored in polyvinyl chloride bags. Historically, plasticizers such as di-(2-ethylhexyl) phthalate (DEHP) were added to preserve the quality of the product, but regulatory bans have led blood services to explore alternative plasticizers. Newer, dried blood components require innovative storage solutions currently ranging from glass containers to plastic bags that are modified to minimize degradation from light and moisture. Innovation in blood components demands innovation in devices for collection and storage, with oversight by accredited bodies for quality assurance.

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Publication Details

Journal
Expert Review of Medical Devices
Published
2026-01-09
DOI
https://doi.org/10.1080/17434440.2026.2615220
Primary Topic
Blood donation and transfusion practices
Type
article
Field-Weighted Citation Impact
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article

Blood transfusion for patients in shock: devices for collection, transport, and storage

Anastazia Keegan, Biswadev Mitra, Charles Wetzel, Kathryn Staughton
Expert Review of Medical Devices
Blood donation and transfusion practices
article

Blood transfusion for patients in shock: devices for collection, transport, and storage

Anastazia Keegan, Biswadev Mitra, Charles Wetzel, Kathryn Staughton
article en

Abstract

Strict maintenance of temperatures is required to ensure the efficacy and safety of blood components. This can be achieved using active or passive transport systems, known as shippers. Additional storage and transportation considerations include pre-conditioning of cold or frozen bricks, packing construct of protective insulating material, location of blood components in shipper, and labeling of blood transport shippers. Blood components are usually collected and stored in polyvinyl chloride bags. Historically, plasticizers such as di-(2-ethylhexyl) phthalate (DEHP) were added to preserve the quality of the product, but regulatory bans have led blood services to explore alternative plasticizers. Newer, dried blood components require innovative storage solutions currently ranging from glass containers to plastic bags that are modified to minimize degradation from light and moisture. Innovation in blood components demands innovation in devices for collection and storage, with oversight by accredited bodies for quality assurance.

Expert Review of Medical DevicesVol. 23(2)
Australian Regenerative Medicine Institute (AU), King Edward Memorial Hospital (AU), The Alfred Hospital (AU), Pathwest Laboratory Medicine (AU), Monash University (AU), Fiji National University (FJ)
Industry, innovation and infrastructure
Openalex Percentile: Top 94%
Blood donation and transfusion practices
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