A conformation-dependent bifunctional fluorescent sensor for viscosity–pH monitoring in oxidative stress models

A conformation-dependent bifunctional sensor is developed by capitalizing on a vibration-induced emission chromophore for viscosity sensing and an acid-triggered oxazolidine switch for pH sensing. This design yields a large Stokes shift (>150 nm), enabling dual-channel and crosstalk-free monitoring of viscosity and pH in oxidative stress models.

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Publication Details

Journal
The Analyst
Published
2026-01-01
DOI
https://doi.org/10.1039/d5an01169h
Primary Topic
Molecular Sensors and Ion Detection
Type
article
Field-Weighted Citation Impact
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article

A conformation-dependent bifunctional fluorescent sensor for viscosity–pH monitoring in oxidative stress models

Lifang Guo, Haijiao Wu, Yuxi Ding, Liying Luo
The Analyst
Molecular Sensors and Ion Detection
article

A conformation-dependent bifunctional fluorescent sensor for viscosity–pH monitoring in oxidative stress models

Lifang Guo, Haijiao Wu, Yuxi Ding, Liying Luo
article en

Abstract

A conformation-dependent bifunctional sensor is developed by capitalizing on a vibration-induced emission chromophore for viscosity sensing and an acid-triggered oxazolidine switch for pH sensing. This design yields a large Stokes shift (>150 nm), enabling dual-channel and crosstalk-free monitoring of viscosity and pH in oxidative stress models.

The AnalystVol. 151(2)
East China University of Science and Technology (CN)
Openalex Percentile: Top 93%
Molecular Sensors and Ion Detection
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A conformation-dependent bifunctional fluorescent sensor for viscosity–pH monitoring in oxidative stress models — Lifang Guo, Haijiao Wu, et al. · The Analyst (2026) | TGRS Research Map | TGRS