An Alternative and Improved Method For the Production of Bornafix

Abstract: Bornafix® by IFF is a fragrance ingredient characterized by warm woody, dry amber, and cedarwood notes. It is used in woody compositions and provides good support for most floral accords. It is substantive and exhibits interesting synergistic properties. This study presents a method for synthesizing this product from iso-borneol and 2-methyl-1,3-propanediol (MPO), catalyzed by naphthalene-1,5-disulfonic acid in benzene. A high yield of 92% was achieved through distillation for product isolation. The results demonstrate an optimized process that enhances the fragrance profile by utilizing readily accessible catalysts while suppressing undesired over-etherification. Furthermore, the developed methodology shows exceptional scalability, establishing itself as a techno-economically viable strategy for industrial manufacturing.

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Publication Details

Journal
Letters in Organic Chemistry
Published
2026-01-07
DOI
https://doi.org/10.2174/0115701786399599251124111032
Primary Topic
Biochemical and biochemical processes
Type
article
Field-Weighted Citation Impact
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article

An Alternative and Improved Method For the Production of Bornafix

Hao Liu, Wenhua Ou, Hui Wang
Letters in Organic Chemistry
Biochemical and biochemical processes
article

An Alternative and Improved Method For the Production of Bornafix

Hao Liu, Wenhua Ou, Hui Wang
article en

Abstract

Abstract: Bornafix® by IFF is a fragrance ingredient characterized by warm woody, dry amber, and cedarwood notes. It is used in woody compositions and provides good support for most floral accords. It is substantive and exhibits interesting synergistic properties. This study presents a method for synthesizing this product from iso-borneol and 2-methyl-1,3-propanediol (MPO), catalyzed by naphthalene-1,5-disulfonic acid in benzene. A high yield of 92% was achieved through distillation for product isolation. The results demonstrate an optimized process that enhances the fragrance profile by utilizing readily accessible catalysts while suppressing undesired over-etherification. Furthermore, the developed methodology shows exceptional scalability, establishing itself as a techno-economically viable strategy for industrial manufacturing.

Letters in Organic ChemistryVol. 23
Shanghai Institute of Technology (CN)
Industry, innovation and infrastructure
Openalex Percentile: Top 93%
Biochemical and biochemical processes
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