Augmented data and neural networks for robust epidemic forecasting: Application to COVID-19 in Italy

In this work, we propose a data augmentation strategy aimed at improving the training phase of neural networks and, consequently, the accuracy of their predictions. Our approach relies on generating synthetic data through a suitable compartmental model combined with the incorporation of uncertainty. Available data are used to calibrate the model, which is further integrated with deep learning techniques to produce additional synthetic data for training. The results show that neural networks trained on these augmented datasets exhibit significantly improved predictive performances. In particular, we focus on two different neural network architectures: Physics-Informed Neural Networks (PINNs) and Nonlinear Autoregressive (NAR) models. The NAR approach proves especially effective for short-term forecasting, thereby providing accurate quantitative estimates by directly learning the dynamics from data and avoiding the additional computational cost of embedding physical constraints into the training. In contrast, PINNs yield less accurate quantitative predictions but capture the qualitative long-term behavior of the system, thus making them more suitable to explore broader dynamical trends. Numerical simulations of the second phase of the COVID-19 pandemic in the Lombardy region (Italy) validate the effectiveness of the proposed approach.

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Publication Details

Journal
Mathematical Biosciences & Engineering
Published
2026-01-01
DOI
https://doi.org/10.3934/mbe.2026019
Primary Topic
COVID-19 epidemiological studies
Type
article
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article

Augmented data and neural networks for robust epidemic forecasting: Application to COVID-19 in Italy

Federica Ferrarese, Giacomo Dimarco, Lorenzo Pareschi
Mathematical Biosciences & Engineering
COVID-19 epidemiological studies
article

Augmented data and neural networks for robust epidemic forecasting: Application to COVID-19 in Italy

Federica Ferrarese, Giacomo Dimarco, Lorenzo Pareschi
article en

Abstract

In this work, we propose a data augmentation strategy aimed at improving the training phase of neural networks and, consequently, the accuracy of their predictions. Our approach relies on generating synthetic data through a suitable compartmental model combined with the incorporation of uncertainty. Available data are used to calibrate the model, which is further integrated with deep learning techniques to produce additional synthetic data for training. The results show that neural networks trained on these augmented datasets exhibit significantly improved predictive performances. In particular, we focus on two different neural network architectures: Physics-Informed Neural Networks (PINNs) and Nonlinear Autoregressive (NAR) models. The NAR approach proves especially effective for short-term forecasting, thereby providing accurate quantitative estimates by directly learning the dynamics from data and avoiding the additional computational cost of embedding physical constraints into the training. In contrast, PINNs yield less accurate quantitative predictions but capture the qualitative long-term behavior of the system, thus making them more suitable to explore broader dynamical trends. Numerical simulations of the second phase of the COVID-19 pandemic in the Lombardy region (Italy) validate the effectiveness of the proposed approach.

Mathematical Biosciences & EngineeringVol. 23(2)
University of Ferrara (IT), Maxwell Institute for Mathematical Sciences (GB)
Good health and well-being
Openalex Percentile: Top 92%
COVID-19 epidemiological studies
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Augmented data and neural networks for robust epidemic forecasting: Application to COVID-19 in Italy — Federica Ferrarese, Giacomo Dimarco, et al. · Mathematical Biosciences & Engineering (2026) | TGRS Research Map | TGRS