Risk of Household Secondary Invasive Group A Streptococcal Infections After a Prophylaxis Policy Change
In this nationwide cohort study, there was a reduction in secondary iGAS risk among household contacts after implementation of an expanded antibiotic prophylaxis policy, which suggests that antibiotic prophylaxis for household contacts of patients with iGAS prevents secondary iGAS infection.
Authors
- Annika van Roon
- Mirjam J. Knol (ORCID: https://orcid.org/0000-0003-0645-5754)
- Bart J. M. Vlaminckx
- Nina M. van Sorge
- Daan W. Notermans
- Hester E. de Melker
- Brechje de Gier
- Margreet J. M. te Wierik
Institutions
- University Medical Center Utrecht (NL)
- National Institute for Public Health and the Environment (NL)
- Amsterdam University Medical Centers (NL)
- University of Amsterdam (NL)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2026-01-08
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.53168
- Citations
- 1
- Primary Topic
- Streptococcal Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 41.85
Funders
- Pfizer
- Argenx
- Amsterdam University Medical Centers
- Fondation Leducq
- ZonMw
- University of California, San Diego