Incidence and Severity of Postacute Sequelae of SARS-CoV-2 Infection in the Omicron Era: A Prospective Cohort Study
In a prospective cohort study of 2,960 non-hospitalized adults with acute SARS-CoV-2 infection, older age, female sex, rural residence, high BMI, greater acute infection severity, chronic lung disease, and poorer general health at baseline were associated with higher risk and severity of postacute sequelae. Recent vaccination was associated with lower postacute sequelae risk and severity, while antiviral therapy was not.
Authors
- W. Fischer
- Jessica Keys (ORCID: https://orcid.org/0000-0001-5093-378X)
- Melissa A Mischell
- Xinyu Zhang (ORCID: https://orcid.org/0000-0001-5000-2483)
- Ning Zhang (ORCID: https://orcid.org/0000-0001-7061-0451)
- Dan-Yu Lin
- Becky Straub
- Dinelka Nanyakkara
- David Wohl
Institutions
- University of North Carolina at Chapel Hill (US)
- Department of Health (ZA)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2026-01-07
- DOI
- https://doi.org/10.1093/infdis/jiag026
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 0.00