On/Off-Discrepancies in medical decision-making: utilising the reversibility of deep brain stimulation to strengthen patient autonomy

Abstract Definition of the problem Some medical interventions have the potential to interfere with patients’ future healthcare decision-making. We identify two types of such influences: affecting whether a patient has decision-making capacity in the first place; and influencing which treatment option a patient ends up selecting. Argument Using the example of deep brain stimulation, we argue that one should utilise this effect to obtain more authentic treatment preferences. In patients with implanted deep brain stimulators who do not meet the capacity threshold, the device state should be reverted as there is a chance that doing so has a positive effect on their capacity. In patients who are already deemed decision-competent, the same approach can reveal on/off-discrepancies in the selection of treatment choices. Conclusion We propose five cross-checking strategies to deal with such discrepancies and call for a revision of current procedures for obtaining consent following any interventions whose psychotropic influences can be reversed within clinically reasonable time frames.

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Publication Details

Journal
Ethik in der Medizin
Published
2026-01-08
DOI
https://doi.org/10.1007/s00481-025-00893-2
Primary Topic
Healthcare Decision-Making and Restraints
Type
article
Field-Weighted Citation Impact
0.00

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article

On/Off-Discrepancies in medical decision-making: utilising the reversibility of deep brain stimulation to strengthen patient autonomy

Aaron D’Sa, Lukas J. Meier
Ethik in der Medizin
Healthcare Decision-Making and Restraints
article

On/Off-Discrepancies in medical decision-making: utilising the reversibility of deep brain stimulation to strengthen patient autonomy

Aaron D’Sa, Lukas J. Meier
article en

Abstract

Abstract Definition of the problem Some medical interventions have the potential to interfere with patients’ future healthcare decision-making. We identify two types of such influences: affecting whether a patient has decision-making capacity in the first place; and influencing which treatment option a patient ends up selecting. Argument Using the example of deep brain stimulation, we argue that one should utilise this effect to obtain more authentic treatment preferences. In patients with implanted deep brain stimulators who do not meet the capacity threshold, the device state should be reverted as there is a chance that doing so has a positive effect on their capacity. In patients who are already deemed decision-competent, the same approach can reveal on/off-discrepancies in the selection of treatment choices. Conclusion We propose five cross-checking strategies to deal with such discrepancies and call for a revision of current procedures for obtaining consent following any interventions whose psychotropic influences can be reversed within clinically reasonable time frames.

Ethik in der Medizin
Mount Auburn Hospital (US), University of Cambridge (GB), Norfolk and Norwich University Hospital (GB), Technical University of Munich (DE)
Harvard University, Fitzwilliam College, University of Cambridge
Peace, Justice and strong institutions
Openalex Percentile: Top 94%
Healthcare Decision-Making and Restraints
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On/Off-Discrepancies in medical decision-making: utilising the reversibility of deep brain stimulation to strengthen patient autonomy — Aaron D’Sa, Lukas J. Meier · Ethik in der Medizin (2026) | TGRS Research Map | TGRS