Defect-rich Mg(OH) <sub>2</sub> nanosheets as high-performance antioxidants
The development of highly efficient radical scavengers remains a substantial challenge in materials chemistry. Here, we report defect-rich Mg(OH)<sub>2</sub> nanosheets (d-Mg(OH)<sub>2</sub>), synthesized via rapid nucleation within a colloid mill, as a potent multifunctional antioxidant. Compared to commercial Mg(OH)<sub>2</sub> (c-Mg(OH)<sub>2</sub>), d-Mg(OH)<sub>2</sub> demonstrates markedly superior scavenging capabilities against a broad spectrum of radicals, including ·O<sub>2</sub>⁻, ·OH, ·NO, DPPH·, and ·Cl. Mechanistic investigations and density functional theory calculations reveal a dual-mode scavenging mechanism: hydrogen atom transfer for ·OH, ·NO, and ·Cl, and electron transfer for ·O<sub>2</sub>⁻ and DPPH·, with significantly reduced energy barriers on the defect-rich surface. We further demonstrate the material’s practical efficacy in scavenging intracellular reactive oxygen species and enhancing the thermal stability of polyvinyl chloride. This work establishes a defect-engineering approach to activate earth-abundant hydroxides as high-performance antioxidants, with promising applications in biomedicine and polymer stabilization.
Authors
- Yiping Ning
- Aijuan Han
- Xulin Zhou
- Xiang Yang
- Yanjun Lin
- Ziyang Liu
- Xue Duan
Publication Details
- Journal
- Nano Research
- Published
- 2026-01-01
- DOI
- https://doi.org/10.26599/nr.2026.94908409
- Primary Topic
- Magnesium Oxide Properties and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Beijing University of Chemical Technology
- State Key Laboratory of Chemical Resource Engineering
- National Synchrotron Radiation Laboratory
- Beijing Synchrotron Radiation Facility