Case report: From metabolic instability to remission: a case of pheochromocytoma presenting as atypical diabetes

This case demonstrates that pheochromocytoma can induce a severe, reversible form of diabetes characterized by profound metabolic instability and marked glycemic variability. It highlights the necessity of including pheochromocytoma in the differential diagnosis of patients with atypical, labile diabetes, especially when paroxysmal symptoms are present. Early surgical intervention can reverse these metabolic derangements, often leading to diabetes remission.

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Publication Details

Journal
Frontiers in Endocrinology
Published
2026-01-09
DOI
https://doi.org/10.3389/fendo.2025.1736477
Primary Topic
Adrenal and Paraganglionic Tumors
Type
article
Field-Weighted Citation Impact
0.00

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article

Case report: From metabolic instability to remission: a case of pheochromocytoma presenting as atypical diabetes

Yuting Xie, Zhiguang Zhou, Chuqing Cao, Xuefeng Yang et al.
Frontiers in Endocrinology
Adrenal and Paraganglionic Tumors
article

Case report: From metabolic instability to remission: a case of pheochromocytoma presenting as atypical diabetes

Yuting Xie, Zhiguang Zhou, Chuqing Cao, Xuefeng Yang, Pingyan Xue, Fansu Huang
article en

Abstract

This case demonstrates that pheochromocytoma can induce a severe, reversible form of diabetes characterized by profound metabolic instability and marked glycemic variability. It highlights the necessity of including pheochromocytoma in the differential diagnosis of patients with atypical, labile diabetes, especially when paroxysmal symptoms are present. Early surgical intervention can reverse these metabolic derangements, often leading to diabetes remission.

Frontiers in EndocrinologyVol. 16
Central South University (CN), Qujing Normal University (CN), Second Xiangya Hospital of Central South University (CN)
National Natural Science Foundation of China, Central South University, Xiangya Hospital, Central South University
Good health and well-being
Openalex Percentile: Top 93%
Adrenal and Paraganglionic Tumors
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