Targeting CXCL8 in post-traumatic stress disorder and Alzheimer’s disease: insights from cross-disorder molecular analysis
Our findings highlight CXCL8-mediated neuroimmune dysregulation as a critical link between PTSD and Alzheimer's disease, supporting targeted anti-inflammatory strategies to mitigate stress-related dementia risk. This study advances a precision medicine framework for neurodegenerative comorbidities by integrating cross-disease molecular signatures.
Authors
- M. Zhang
- T. Li
- Zixuan Cao
- Qiuzi Yang
- Xin Li
- Dan Liu
- Xia Li
- Zhicheng Tian
- Peng Luo
Institutions
- Xijing Hospital (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2026-01-09
- DOI
- https://doi.org/10.1080/07853890.2025.2610559
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00