Low-Load Blood Flow Restriction Training as an Alternative to Heavy-Load Resistance Training in Early-Stage Rehabilitation Following Bone-Patellar Tendon-Bone ACL Reconstruction: A Randomized Controlled Trial

OBJECTIVE: To compare the effects of low-load blood flow restriction training (LL-BFRT) and heavy-load resistance training (HLRT) on quadriceps and hamstring strength, knee pain, joint effusion, and range of motion following bone-patellar tendon-bone (BPTB) anterior cruciate ligament (ACL) reconstruction. DESIGN: Randomized controlled trial. METHODS: LL-BFRT and HLRT included 12 weeks of biweekly strength training. Quadriceps and hamstring strength, measured in Newton-meters per kilogram, was assessed at 60°/s, 180°/s and 300°/s at baseline and final follow-up. At final follow-up, knee pain, joint effusion, and range of motion deficits were assessed. RESULTS: Of 28 patients, 23 completed the study. Study groups were comparable at baseline. At final follow-up, no significant differences were observed in quadriceps strength at 60°/s (2.7 and 3.1, p = 0.738, 180°/s (2.3 and 2.8, p = 0.387) and 300°/s (2.2 and 2.8, p = 0.387) as well as in hamstring strength at 60°/s (3.2 and 3.1, p = 0.738), 180°/s (3.2 and 2.9, p = 0.738) and 300°/s (2.8 and 2.6, p = 0.738) for the LL-BFRT and HLRT group, respectively. Similarly, no significant differences were found for knee pain (14.3% and 35.7%, p = 0.380), joint effusion (7.1% and 35.7%, p = 0.444), flexion deficit (7.1% and 28.6%, p = 0.426) and extension deficit (0.0% and 14.3%, p = 0.478). CONCLUSION: LL-BFRT in the early phase of rehabilitation following BPTB ACL reconstruction demonstrated similar muscle strength, knee pain, joint effusion, and range of motion compared with HLRT. These results support LL-BFRT as a safe alternative when HLRT cannot be performed.

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Journal
JOSPT open.
Published
2026-01-08
DOI
https://doi.org/10.2519/josptopen.2026.0185
Primary Topic
Cardiovascular and exercise physiology
Type
article
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article

Low-Load Blood Flow Restriction Training as an Alternative to Heavy-Load Resistance Training in Early-Stage Rehabilitation Following Bone-Patellar Tendon-Bone ACL Reconstruction: A Randomized Controlled Trial

Baris B. Koc, Martijn G.M. Schotanus, Alexander Truyens, Rob de Bie et al.
JOSPT open.
Cardiovascular and exercise physiology
article

Low-Load Blood Flow Restriction Training as an Alternative to Heavy-Load Resistance Training in Early-Stage Rehabilitation Following Bone-Patellar Tendon-Bone ACL Reconstruction: A Randomized Controlled Trial

Baris B. Koc, Martijn G.M. Schotanus, Alexander Truyens, Rob de Bie, E.J. Jansen, Tom Ehlen
article en

Abstract

OBJECTIVE: To compare the effects of low-load blood flow restriction training (LL-BFRT) and heavy-load resistance training (HLRT) on quadriceps and hamstring strength, knee pain, joint effusion, and range of motion following bone-patellar tendon-bone (BPTB) anterior cruciate ligament (ACL) reconstruction. DESIGN: Randomized controlled trial. METHODS: LL-BFRT and HLRT included 12 weeks of biweekly strength training. Quadriceps and hamstring strength, measured in Newton-meters per kilogram, was assessed at 60°/s, 180°/s and 300°/s at baseline and final follow-up. At final follow-up, knee pain, joint effusion, and range of motion deficits were assessed. RESULTS: Of 28 patients, 23 completed the study. Study groups were comparable at baseline. At final follow-up, no significant differences were observed in quadriceps strength at 60°/s (2.7 and 3.1, p = 0.738, 180°/s (2.3 and 2.8, p = 0.387) and 300°/s (2.2 and 2.8, p = 0.387) as well as in hamstring strength at 60°/s (3.2 and 3.1, p = 0.738), 180°/s (3.2 and 2.9, p = 0.738) and 300°/s (2.8 and 2.6, p = 0.738) for the LL-BFRT and HLRT group, respectively. Similarly, no significant differences were found for knee pain (14.3% and 35.7%, p = 0.380), joint effusion (7.1% and 35.7%, p = 0.444), flexion deficit (7.1% and 28.6%, p = 0.426) and extension deficit (0.0% and 14.3%, p = 0.478). CONCLUSION: LL-BFRT in the early phase of rehabilitation following BPTB ACL reconstruction demonstrated similar muscle strength, knee pain, joint effusion, and range of motion compared with HLRT. These results support LL-BFRT as a safe alternative when HLRT cannot be performed.

JOSPT open.
Zuyderland Medisch Centrum (NL)
Good health and well-being
Openalex Percentile: Top 92%
Cardiovascular and exercise physiology
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Low-Load Blood Flow Restriction Training as an Alternative to Heavy-Load Resistance Training in Early-Stage Rehabilitation Following Bone-Patellar Tendon-Bone ACL Reconstruction: A Randomized Controlled Trial — Baris B. Koc, Martijn G.M. Schotanus, et al. · JOSPT open. (2026) | TGRS Research Map | TGRS