De-escalation of axillary surgery after neoadjuvant therapy in breast cancer: long-term outcomes of sentinel lymph node biopsy alone versus complete axillary lymph node dissection

SLNB alone achieves oncologic outcomes comparable to ALND in ycN0 breast cancer patients after NST, regardless of initial nodal status, with caution warranted in initial cN2-3 disease. This suggests that SLNB alone can safely substitute ALND without compromising oncologic outcomes in appropriately selected patients.

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Publication Details

Journal
Therapeutic Advances in Medical Oncology
Published
2026-01-01
DOI
https://doi.org/10.1177/17588359251405095
Citations
1
Primary Topic
Breast Cancer Treatment Studies
Type
article
Field-Weighted Citation Impact
24.82
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article

De-escalation of axillary surgery after neoadjuvant therapy in breast cancer: long-term outcomes of sentinel lymph node biopsy alone versus complete axillary lymph node dissection

Haizhu Chen, Xiujuan Gui, Qiang Liu, Xiaoyan Qian et al.
1 citations
Therapeutic Advances in Medical Oncology
Breast Cancer Treatment Studies
24.82
article

De-escalation of axillary surgery after neoadjuvant therapy in breast cancer: long-term outcomes of sentinel lymph node biopsy alone versus complete axillary lymph node dissection

Haizhu Chen, Xiujuan Gui, Qiang Liu, Xiaoyan Qian, Yunxia Tao, Luhui Mao, H. Yao, Yaping Yang
article en
1 citations

Abstract

SLNB alone achieves oncologic outcomes comparable to ALND in ycN0 breast cancer patients after NST, regardless of initial nodal status, with caution warranted in initial cN2-3 disease. This suggests that SLNB alone can safely substitute ALND without compromising oncologic outcomes in appropriately selected patients.

Therapeutic Advances in Medical OncologyVol. 18
Sun Yat-sen University (CN), Xuzhou Medical College (CN), Sun Yat-sen Memorial Hospital (CN), Henan Provincial People's Hospital (CN)
Openalex Percentile: Top 3%
Breast Cancer Treatment Studies
24.82
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De-escalation of axillary surgery after neoadjuvant therapy in breast cancer: long-term outcomes of sentinel lymph node biopsy alone versus complete axillary lymph node dissection — Haizhu Chen, Xiujuan Gui, et al. · Therapeutic Advances in Medical Oncology (2026) | TGRS Research Map | TGRS