The DEAD-box RNA helicase eIF4A is a crucial factor for stem-cell activity and reproduction of the parasite Schistosoma mansoni

Our results suggest that SmeIF4A-a is a key factor in stem-cell proliferation and gonad maintenance, and thus also in egg production.

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Publication Details

Journal
Frontiers in Cellular and Infection Microbiology
Published
2026-01-09
DOI
https://doi.org/10.3389/fcimb.2025.1731808
Primary Topic
PI3K/AKT/mTOR signaling in cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

The DEAD-box RNA helicase eIF4A is a crucial factor for stem-cell activity and reproduction of the parasite Schistosoma mansoni

F. Magari, Simone Haeberlein, Oliver Puckelwaldt, Christoph Gero Grevelding et al.
Frontiers in Cellular and Infection Microbiology
PI3K/AKT/mTOR signaling in cancer
article

The DEAD-box RNA helicase eIF4A is a crucial factor for stem-cell activity and reproduction of the parasite Schistosoma mansoni

F. Magari, Simone Haeberlein, Oliver Puckelwaldt, Christoph Gero Grevelding, Sagar Ajmera, Sophie Welsch, Arnold Grünweller
article en

Abstract

Our results suggest that SmeIF4A-a is a key factor in stem-cell proliferation and gonad maintenance, and thus also in egg production.

Frontiers in Cellular and Infection MicrobiologyVol. 15
Philipps University of Marburg (DE), Justus-Liebig-Universität Gießen (DE)
Responsible consumption and production
Openalex Percentile: Top 93%
PI3K/AKT/mTOR signaling in cancer
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