Sequential salvage systemic therapy after immunotherapy in head and neck cancer: a real-world study

Cetuximab-based SCAI post-ICI showed high rates of response, which were durable and profound, and improved survival compared to historical data, with modest efficacy in re-sequenced patients. Time on cetuximab was significantly longer than on ICI. These results should be confirmed in a larger prospective study.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-01-09
DOI
https://doi.org/10.3389/fonc.2025.1719793
Primary Topic
Head and Neck Cancer Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Sequential salvage systemic therapy after immunotherapy in head and neck cancer: a real-world study

Salomé Merino-Menéndez, Santiago Cabezas-Camarero, M. A. P. Sotelo, Pablo Pérez-Alonso et al.
Frontiers in Oncology
Head and Neck Cancer Studies
article

Sequential salvage systemic therapy after immunotherapy in head and neck cancer: a real-world study

Salomé Merino-Menéndez, Santiago Cabezas-Camarero, M. A. P. Sotelo, Pablo Pérez-Alonso, María Nieves Cabrera-Martín
article en

Abstract

Cetuximab-based SCAI post-ICI showed high rates of response, which were durable and profound, and improved survival compared to historical data, with modest efficacy in re-sequenced patients. Time on cetuximab was significantly longer than on ICI. These results should be confirmed in a larger prospective study.

Frontiers in OncologyVol. 15
Villa Maria Hospital (UG), Hospital Clínico San Carlos (ES), Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (ES), EsSALUD (PE), Centro Peruano de Estudios Sociales (PE), Molecular Oncology (United States) (US)
Good health and well-being
Openalex Percentile: Top 93%
Head and Neck Cancer Studies
DOIOpen Access PDFOpenAlex
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Sequential salvage systemic therapy after immunotherapy in head and neck cancer: a real-world study — Salomé Merino-Menéndez, Santiago Cabezas-Camarero, et al. · Frontiers in Oncology (2026) | TGRS Research Map | TGRS