Control Signals in Closed-Loop Spinal Cord Stimulation in Patients with Chronic Pain: A Scoping Review
A closed-loop SCS algorithm that incorporates subjective and objective features may hold potential to improve quality of life in patients with chronic pain. Combining these approaches in a temporally resolved manner, for example, integrating patient reports with continuous electrophysiologic information using a state space mathematical model, could allow more optimized and patient-specific SCS programming.
Authors
- Suguna. Pappu
- Brian Y. Hong
- Ravishankar K. Iyer (ORCID: https://orcid.org/0000-0003-2245-3038)
- Ying Yang (ORCID: https://orcid.org/0009-0000-5441-6691)
- Prateek Dullur (ORCID: https://orcid.org/0009-0005-2094-4038)
- Meenakshi Singhal
- Mehreen Ali
Institutions
- Carle Foundation Hospital (US)
- University of Illinois Urbana-Champaign (US)
- Illinois College (US)
Publication Details
- Journal
- Neuromodulation Technology at the Neural Interface
- Published
- 2026-01-01
- DOI
- https://doi.org/10.1016/j.neurom.2025.11.011
- Primary Topic
- Pain Management and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science Foundation