Gamma heavy-chain disease presenting with hypercalcaemia and ascites

Consider gamma heavy-chain disease in patients with unexplained monoclonal gammopathy and atypical presentations, such as hypercalcaemia and ascites.A combination of rituximab and chemotherapy shows an anti-tumour effect in gamma heavy-chain disease expressing CD20.

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Publication Details

Journal
European Journal of Case Reports in Internal Medicine
Published
2026-01-09
DOI
https://doi.org/10.12890/2026_005987
Primary Topic
Amyloidosis: Diagnosis, Treatment, Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Gamma heavy-chain disease presenting with hypercalcaemia and ascites

Pauline Lionne, L. Terriou, Imane El Boutahiri, Kmar Mrad
European Journal of Case Reports in Internal Medicine
Amyloidosis: Diagnosis, Treatment, Outcomes
article

Gamma heavy-chain disease presenting with hypercalcaemia and ascites

Pauline Lionne, L. Terriou, Imane El Boutahiri, Kmar Mrad
article en

Abstract

Consider gamma heavy-chain disease in patients with unexplained monoclonal gammopathy and atypical presentations, such as hypercalcaemia and ascites.A combination of rituximab and chemotherapy shows an anti-tumour effect in gamma heavy-chain disease expressing CD20.

European Journal of Case Reports in Internal MedicineVol. 13(2)
Université de Lille (FR), Centre de Référence des Maladies Autoinflammatoires et des Amyloses (FR), Centre Hospitalier d'Arras (FR), Université Lille Nord de France (FR)
Good health and well-being
Openalex Percentile: Top 93%
Amyloidosis: Diagnosis, Treatment, Outcomes
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