Risk for coronary artery disease among individuals with normal low-density lipoprotein cholesterol (LDL-C) levels
Individuals with 'normal' LDL-C levels can have substantial CAD risk if they carry high genetic risk. These findings underscore the importance of incorporating genetic information into CAD risk assessment, even among those with traditionally normal lipid profiles.
Authors
- Henry M. Dunnenberger
- Arman Qamar
- David Duggan
- Jianfeng Xu (ORCID: https://orcid.org/0000-0001-5592-3265)
- Jun Wei
- David Davidson
- PETER HULICK
- A R Sanders
- Annabelle Ashworth
- SLilly Zheng
- Huy Gia Tran
- Zhuqing Shi
- Ashley J. Mulford
Institutions
- Translational Genomics Research Institute (US)
- NorthShore University HealthSystem (US)
- University of Chicago (US)
- Evanston Hospital (US)
- Center for Genomic Science (IT)
- Genomic Health (United States) (US)
Publication Details
- Journal
- International Journal of Cardiology Cardiovascular Risk and Prevention
- Published
- 2026-01-08
- DOI
- https://doi.org/10.1016/j.ijcrp.2026.200572
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00