VAMP7‐mediated autophagy regulates cervical cancer progression associated with persistent HPV16 infection

VAMP7 displays dynamic expression changes during HPV16-associated cervical lesion progression. VAMP7 promotes malignant phenotypes of cervical cancer cells by regulating autophagic flux via SNARE-mediated vesicle fusion. Dysregulated VAMP7-mediated autophagy contributes to cervical carcinogenesis in an HPV16-associated context.

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Publication Details

Journal
Clinical and Translational Medicine
Published
2026-01-01
DOI
https://doi.org/10.1002/ctm2.70590
Primary Topic
Autophagy in Disease and Therapy
Type
article
Field-Weighted Citation Impact
0.00
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article

VAMP7‐mediated autophagy regulates cervical cancer progression associated with persistent HPV16 infection

Weijuan Xin, Jing Zhang, Yiying Cai, Yue Wang et al.
Clinical and Translational Medicine
Autophagy in Disease and Therapy
article

VAMP7‐mediated autophagy regulates cervical cancer progression associated with persistent HPV16 infection

Weijuan Xin, Jing Zhang, Yiying Cai, Yue Wang, Zhiling Zhu, Hua Keqin, Xue Ding, Na Liu, Lu Zhou, Dan Wu
article en

Abstract

VAMP7 displays dynamic expression changes during HPV16-associated cervical lesion progression. VAMP7 promotes malignant phenotypes of cervical cancer cells by regulating autophagic flux via SNARE-mediated vesicle fusion. Dysregulated VAMP7-mediated autophagy contributes to cervical carcinogenesis in an HPV16-associated context.

Clinical and Translational MedicineVol. 16(1)
Tongji University (CN), Shanghai Medical Information Center (CN), Obstetrics and Gynecology Hospital of Fudan University (CN), Tongji Hospital (CN), Dezhou University (CN)
Openalex Percentile: Top 94%
Autophagy in Disease and Therapy
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