Proteomic and Genetic Insights into Ancestry‐Specific Associations in Parkinson's Disease

This cross-ancestry proteogenomic analysis reveals shared and ancestry-specific proteomic signatures causally linked to PD, underscoring the importance of using ancestry-aware analytical frameworks to discover robust biomarkers and novel therapeutic targets. © 2026 International Parkinson and Movement Disorder Society.

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Publication Details

Journal
Movement Disorders
Published
2026-01-08
DOI
https://doi.org/10.1002/mds.70169
Primary Topic
Parkinson's Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Proteomic and Genetic Insights into Ancestry‐Specific Associations in Parkinson's Disease

Shen‐Yang Lim, M. Renteria, Ai Huey Tan, Elaine Guo‐Yan Chew et al.
Movement Disorders
Parkinson's Disease Mechanisms and Treatments
article

Proteomic and Genetic Insights into Ancestry‐Specific Associations in Parkinson's Disease

Shen‐Yang Lim, M. Renteria, Ai Huey Tan, Elaine Guo‐Yan Chew, Jia‐Nee Foo, Liang‐Dar Hwang, Jue‐Sheng Ong, Amanda Wei‐Yin Lim
article en

Abstract

This cross-ancestry proteogenomic analysis reveals shared and ancestry-specific proteomic signatures causally linked to PD, underscoring the importance of using ancestry-aware analytical frameworks to discover robust biomarkers and novel therapeutic targets. © 2026 International Parkinson and Movement Disorder Society.

Movement Disorders
University Malaya Medical Centre (MY), The University of Queensland (AU), Nanyang Technological University (SG), QIMR Berghofer Medical Research Institute (AU), University of Malaya (MY), Genome Institute of Singapore (SG)
Rebecca L. Cooper Medical Research Foundation, Medical Research Council, National Health and Medical Research Council
Openalex Percentile: Top 92%
Parkinson's Disease Mechanisms and Treatments
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