Which clinical factors and biochemical parameters differentiate major depressive disorder with versus without lifetime psychotic symptoms?

Lifetime psychotic symptoms confer a more severe course of illness in patients with MDD. No biochemical parameter resulted as a biomarker of MDD psychotic subtype.

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Publication Details

Journal
International Journal of Psychiatry in Clinical Practice
Published
2026-01-09
DOI
https://doi.org/10.1080/13651501.2025.2611928
Primary Topic
Tryptophan and brain disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Which clinical factors and biochemical parameters differentiate major depressive disorder with versus without lifetime psychotic symptoms?

Enrico Capuzzi, Jennifer L. Barkin, Antonios Dakanalis, Alessandro Ceresa et al.
International Journal of Psychiatry in Clinical Practice
Tryptophan and brain disorders
article

Which clinical factors and biochemical parameters differentiate major depressive disorder with versus without lifetime psychotic symptoms?

Enrico Capuzzi, Jennifer L. Barkin, Antonios Dakanalis, Alessandro Ceresa, F Legnani, Guido Nosari, Ilaria Tagliabue, Cecilia Maria Esposito, Martina Di Paolo, Teresa Surace, Luisa Cirella
article en

Abstract

Lifetime psychotic symptoms confer a more severe course of illness in patients with MDD. No biochemical parameter resulted as a biomarker of MDD psychotic subtype.

International Journal of Psychiatry in Clinical Practice
Mercer University (US), University of Milan (IT), Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT), Mental Health Foundation (GB), Ospedale Maggiore (IT), University of Milano-Bicocca (IT)
Good health and well-being
Openalex Percentile: Top 90%
Tryptophan and brain disorders
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