Defining positivity in the lymphocyte transformation test with cytokine read-out: What is the best of bad choices?
We encourage researchers working with the LTT with IFN-γ or another cytokine read-out to test different statistical approaches on their raw data to explore how the different approaches perform.
Authors
- Stefanie Röseler
- Leonie Weinhold (ORCID: https://orcid.org/0000-0002-9194-9427)
- Bernhardt Sachs (ORCID: https://orcid.org/0000-0001-8260-0891)
- Diana Dubrall (ORCID: https://orcid.org/0000-0002-8763-051X)
- Gerda Wurpts
- Caspar A. Heubach
- Andreas Glässner
- Markus Nöthen
- Philipp Deck
- Günther Weindl
- Amir S. Yazdi
Institutions
- Federal Institute for Drugs and Medical Devices (DE)
- University of Bonn (DE)
- Zimmer Biomet (Netherlands) (NL)
- University Hospital Bonn (DE)
- RWTH Aachen University (DE)
Publication Details
- Journal
- Journal of Immunological Methods
- Published
- 2026-01-09
- DOI
- https://doi.org/10.1016/j.jim.2026.114035
- Primary Topic
- Advanced Biosensing Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00