Combination Therapy with Oral Doxycycline and Intradermal Botulinum Toxin Type A for Moderate-to-Severe Rosacea: A Randomized Controlled Trial
The combination of oral doxycycline and intradermal BTX is more effective than doxycycline monotherapy in reducing erythema, flushing, and inflammatory lesions in moderate-to-severe rosacea, with a comparable safety profile. This combination therapy offers a promising approach for comprehensive management of rosacea symptoms.
Authors
- 篤幸 設楽
- Minh Nguyet Vu (ORCID: https://orcid.org/0000-0001-5025-0209)
- Luong Huy Vu (ORCID: https://orcid.org/0009-0000-1106-4673)
- Tuyen T. Nguyen (ORCID: https://orcid.org/0000-0003-1732-4928)
- Hoan Vu
- Phuong T. M. Pham
Institutions
- Hanoi Medical University (VN)
- Vietnam National Children's Hospital (VN)
Publication Details
- Journal
- Indian Journal of Dermatology
- Published
- 2026-01-09
- DOI
- https://doi.org/10.4103/ijd.ijd_654_24
- Primary Topic
- Acne and Rosacea Treatments and Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00