Integrated bioinformatic identification and translational validation of key biomarkers and therapeutic candidates for preeclampsia-related acute kidney injury
IL-6, CXCL2, and CEBPB are identified as key mediators in PE-AKI. Among them, CXCL2 and CEBPB show particular promise as diagnostic biomarkers, a finding that warrants further validation in larger, multi-center cohorts to confirm their utility in stratifying disease severity.
Authors
- Ke Liu (ORCID: https://orcid.org/0000-0001-5875-6095)
- Xiaohui Liu (ORCID: https://orcid.org/0000-0002-3670-1752)
- Lina Gao
- De Chen
- Dong Yan
- Xiaoling Liu
Institutions
- Gansu Provincial Maternal and Child Health Hospital (CN)
- Lanzhou City University (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Archives of Gynecology and Obstetrics
- Published
- 2026-01-08
- DOI
- https://doi.org/10.1007/s00404-025-08282-2
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00