Proteomics analysis of human mesenchymal stromal/stem cell sarcomagenesis model identifies ALDH1A3 and CD99 as potential targets in the transformation process
Proteomics investigation of a MSC-transformation model of sarcoma has yielded ALDH1A3 and CD99 as potential targets for sarcomagenesis that may contribute to a greater understanding of the disease and the development of novel therapeutic approaches.
Authors
- Michael Rosu‐Myles (ORCID: https://orcid.org/0000-0003-2264-6905)
- Mercedes Guerrero-Murillo (ORCID: https://orcid.org/0000-0002-5556-2460)
- Gauri Muradia
- Jonathan Gobin (ORCID: https://orcid.org/0009-0007-0186-4213)
- Verónica Rey (ORCID: https://orcid.org/0000-0001-9362-1700)
- Hala Halabi
- Pablo Menendez
- Jessie R. Lavoie
- Rene Rodriguez
- Juan Tornín
- Clara Bueno
- Jun Gao
- Belen Lopez-Millan
Institutions
- Health Canada (CA)
- University of Ottawa (CA)
- Instituto de Salud Carlos III (ES)
- Josep Carreras Leukaemia Research Institute (ES)
- Red de Investigación en Sida (ES)
- Centro de Investigación Biomédica en Red de Cáncer (ES)
- Instituto de Investigación Sanitaria del Principado de Asturias (ES)
- Universitat de Barcelona (ES)
Publication Details
- Journal
- BMC Biology
- Published
- 2026-01-09
- DOI
- https://doi.org/10.1186/s12915-025-02498-z
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 0.00